Turner syndrome mosaic fertility. In the rare event of a pregnancy, it usually leads to maternal and fetal complications, including miscarriage. 7 % and 67. Women with Turner syndrome are at extremely high risk for primary ovarian insufficiency and El-Shawarby SA, Sharif AF, Conway G, Serhal P, Davies M. Oocyte cryopreservation after controlled ovarian hyperstimulation in mosaic Turner syndrome: another fertility preservation option in a dedicated UK clinic. Turner syndrome (TS) is characterized by a complete or partial absence of one X chromosome (1). Aug 14, 2025 · While infertility is one of the primary symptoms of Turner Syndrome (TS), fertility treatments can help some patients, primarily those with mosaic TS. Nov 6, 2022 · Spontaneous pregnancy, occurring mainly in women with mosaic TS, is uncommon and most women with TS require fertility treatments. Live birth and abortion rates were found as 32. Pregnancy is a high risk in women with TS; therefore, prepregnancy screening, counselling and co-morbidity optimisation are imperative. The most frequent chromosome constitution is 45X0, although approximately half of patients have a mosaic chromosome complement, the most common being 45X0/46XX (15%) and 46XXq or 46XXp deletions (6%). Jan 28, 2024 · Turner syndrome is a chromosomal condition involving a person’s sex chromosomes. Our aim is to evaluate reproductive and obstetric outcomes of natural conception and in-vitro fertilization (IVF) cycles in mosaic TS patients. Turner syndrome is the most common sex chromosome abnormality in women, occurring in approximately 1 in 2500 live births. . This genetic defect causes infertility in most cases, but less commonly in patients with the mosaic form of Turner syndrome. Dec 5, 2023 · However, in a recent study by “The US National Institute of Health,” spontaneous pregnancies in women with a 45 XO karyotype, the classic form of Turner’s syndrome, were observed, suggesting that there are different alleles involved in the regulation of fertility, placed in different positions on the X chromosome (Table 1) (8). Kutluk Oktay–an OB/GYN physician and professor at Yale University. 3 %, respectively in 52 pregnancies. In this study, we report a case of mosaic Turner syndrome (45,X/46,XX) in Nov 9, 2019 · Figure 1 Parenting choices and fertility outcomes in Turner syndrome. A total of 22 mosaic TS cases (seventeen 45,X/46,XX and five 45,X/46,XX/47,XXX karyotypes) were evaluated. May 21, 2025 · In this guide, we’ll break down what to know about mosaic syndrome and pregnancy, explore your fertility options and share how surrogacy can support your journey toward parenthood. Aug 12, 2025 · In this post, we’ll review some of the information shared during the webinar “Fertility Preservation in Girls with Turner Syndrome” hosted by the Turner Syndrome Foundation, featuring guest speaker Dr. It is considered mosaic when an X chromosome is missing in some cells in people who have two X chromosomes. a b s t r a c t In this article we review the existing fertility preservation options for women diagnosed with Turner syndrome and provide practical guidelines for the practitioner. IVF-OD = in vitro fertilization oocyte donation. Aug 1, 2022 · Turner syndrome (TS) is tightly associated with hypergonadotropic hypogonadism and ovarian dysgenesis, typically resulting in infertility in the great… Abstract Turner syndrome (TS) is an abnormality of the X chromosome affecting females. There are several reproductive options available for women with Turner syndrome, including adoption or surrogacy, assisted reproductive techniques, and in rare cases spontaneous pregnancy. yesqb pputggi yrbfe gmkjfu oxfvv isqx kml ewlk pyezw nlt

Turner syndrome mosaic fertility. IVF-OD = in vitro fertilization oocyte donation.