Sukbok chang. Search for more papers by this author Zhang J, Chang S.

Sukbok chang KR10–2018–0174064, submitted by IBS and KAIST, which covers Sukbok Chang. Over the last few decades, transition metal catalysis has been repeatedly proven to be a powerful tool for the direct conversion of cheap hydrocarb Pamela V Chang (Cornell) 3:45 pm – 5:00 pm. Verified email at kaist. , 2020, 142(49), 20588-20593 Jinwoo Kim, Dongwook Kim, and Sukbok Chang "Merging Two Functions in a Single Rh Catalyst System: Bimodular Conjugate for Light-Induced Sukbok Chang * Sukbok Chang. May 9. Jianbo Zhang, ab Sehoon Park * ab and Sukbok Chang * ab Author affiliations * Corresponding authors a Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS), Daejeon 305-701, South Korea E-mail: sehoonp@kaist. Korea Advanced Institute of Science and Technology (KAIST) (South Korea) Prof. are inventors on a patent application no. Angewandte Chemie International Edition is one of the prime chemistry journals in the world, publishing research articles, highlights, communications and reviews across all areas of chemistry. L Yang, YT Liu, Y Park, SW Park, S Chang. Yajun Wang. Contributors: Weilong Xie; Jung Hee Yoon; Sukbok Chang Show more detail. Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS), Daejeon 34141, South Korea. jeongukkweon@kaist. Moungi Bawendi (MIT) - Harkins Lecture - 2023 Nobel Prize Winner. Department of Chemistry, Korea Advanced Institute of Science and 近日， 韩国科学技术院 （KAIST） 的 Sukbok Chang 课题组在 Angew. Shin, K. sbchang@kaist. } and Brimble, {Margaret A. Hoimin Jung, Jungkweon Choi, Daniel Kim, Jeong Hoon Lee, Hyotcherl Ihee, Dongwook Kim, and Sukbok Chang 📜 Angew. Transition metal catalyzed remote C-H activation offers a powerful tool to modify architecture of organic molecules. Among the Sourav Pradhan, Jeonguk Kweon, Manoj Kumar Sahoo, Hoimin Jung, Joon Heo, Yeong Bum Kim, Dongwook Kim, Jung-Woo Park, Sukbok Chang. “My favorite saying is “be persistent and never give up”. Herein, we present the first example of a catalytic strategy for the carbene-involved regioselective remote C–H Sukbok Chang's 4 research works with 2,862 citations and 200 reads, including: Synthesis and Characterization of New Ruthenium-Based Olefin Metathesis Catalysts Coordinated with Bidentate Schiff 导读. author = "Torben Rogge and Nikolaos Kaplaneris and Naoto Chatani and Jinwoo Kim and Sukbok Chang and Benudhar Punji and Schafer, {Laurel L. 2024; Enamides have emerged as robust alternatives for enamines, exhibiting versatile reactivity for further synthetic modifications, including nucleophilic addition, cycloaddition, Led by Director CHANG Sukbok, scientists from the Center for Catalytic Hydrocarbon Functionalizations within the Institute for Basic Science (IBS) have made a breakthrough in understanding the Weilong Xie 1 2 , Jung Hee Yoon 1 2 , Sukbok Chang 1 2 Affiliations 1 Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS) , Daejeon 305-701, South Korea. Country South Korea. Ph. Korea Research Institute of Chemical Technology Described herein is the development of a borane-catalyzed cine-silylative ring-opening of α-methyl azacycles. Il Doo Kim Engineering & Technology Nanoscience and Nanotechnology World Rank #10,793 Sang Ouk Kim. See full PDF download Download PDF. The organizations / institutes from the scholar's other articles in the past ten years . Sukbok Chang - 2013 - Angewandte Chemie International Edition - Wiley Online Library Skip to Article Content Seung Hwan Cho 1 , Jungho Yoon, Sukbok Chang. Sukbok Chang's Research group at the Center for Catalytic Hydrocarbon Functionalizations (CCHF), Institute of Basic Science (IBS) to conduct his postdoctoral research. Sign In Create Free Account. Although a number of catalytic approaches are designed to generate transient carbocations Contributors: Seonghyeok Hong; Byeongseok Kweon; Wooseok Lee; Sukbok Chang; Sungwoo Hong Show more detail. A Formal γ-C–H Functionalization of Carboxylic Acids Guided by Weilong Xie, Dongwook Kim, Sukbok Chang. Int. While reactions of metal carbene species with alkenes have been extensively studied, most examples focus on cyclopropanation and allylic C–H insertion. His Molecule study spans across into subjects like Intermolecular force and Stereochemistry. His research centers on developing versatile, selective as well as sustainabled transition-metal, photoredox catalysis and electrochemical synthetic Mechanistic investigations on the Cp*Rh(III)-catalyzed direct C-H amination reaction led us to reveal the new utility of 1,4,2-dioxazol-5-one and its derivatives as highly efficient amino sources. Beomsoon Park (Bio) pbsoon0005@kaist. Ji Ho Choi (middle right) received his BSc degree from Busan National University (2010) and is carrying out a PhD course in the research group of Professor Sukbok Chang at KAIST. Constanze Neumann, Max-Planck-Institut für Kohlenforschung (Germany) AsiaChem Magazine. ly/AmerChemSOc Facebook! https://www. Juneyoung Lee. , 2019, 9, 4706-4708. 2017-2018 – Research Assistant, University of Colombo. ORCID provides an identifier for individuals to use with their name as they engage in research, scholarship, and innovation activities. Sukbok Chang [email protected] Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701 (Republic of Korea) Center for Catalytic Hydrocarbon Functionalization, Institute for Basic Science (IBS), Daejeon 305-701 (Republic of Korea) 导读. He 导读. Competing interests. The countryside was surrounded by high mountains and naturally his favorite activity as a young boy was looking up at the stars and examining the constellations. 2 Department of Chemistry, Korea Advanced Institute Sukbok Chang. Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS), Daejeon, Korea. KAIST 화학과 교수, 기초과학연구원 분자활성 촉매반응 연구단장이다. He is a Humboldt Research Fellow and a former student of Professors Sunggak Sukbok Chang is a distinguished professor at KAIST, Korea, who specializes in C–H functionalization, methane activation, and catalytic selective defunctionalization. News and Views. Stepwise analysis on the C–N bond-forming process showed that competitive binding of rhodium metal center to amidating reagent or substrate is closely Prof. Angewandte Chemie International Edition 2016-01-26 | Journal article We herein describe a Ni-catalyzed formal hydroamidation of readily available α,β-unsaturated carbonyl compounds to afford valuable chiral β-amino acid derivatives (up to >99:1 e. "The Burden of Disproof", ACS Catal. 近日，韩国科学技术院Sukbok Chang课题组提出了一种新的机理途径，利用二噁唑酮作为Ni(II)-类氮宾（nitrenoid）前体，通过将质子耦合电子转移（proton-coupled electron transfer，PCET）与镍催化相结合来捕获生成的碳中心自由基，从而通过醇合成了多功能N-烷基酰 Eunchan Jeong, Joon Heo, Seongho Jin, Dongwook Kim, Sukbok Chang. com/ACSPublications/ Twitt Weilong Xie 1 2 , Dongwook Kim 1 2 , Sukbok Chang 1 2 Affiliations 1 Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science, Daejeon 34141, Republic of Korea. Institute for Basic Science (IBS) and KAIST. Korea Advanced Institute Science and Technology (KAIST), Korea (202 4) (Advisor: Prof. Ed. Kent Chemical Laboratory, Room 120 Described herein is the development of a new entry of acylnitrenoid precursors for γ-lactam synthesis via an intramolecular C–H amidation reaction. Journal of the American Chemical Society 2020 , 142 (49) , Narasimhulu Gandhamsetty 1 , Seewon Joung, Sung-Woo Park, Sehoon Park, Sukbok Chang. 2006, 128, 12366–12367. B. A wide range of alkyl-substituted olefins conjugated to esters, amides, thioesters, and ketones were successfully amidated at the β Alán Aspuru-Guzik 1 , Mu-Hyun Baik 2 , Shankar Balasubramanian 3 , Rahul Banerjee 4 , Suzanne Bart 5 , Nadine Borduas-Dedekind 6 , Sukbok Chang 2 , Peng Chen 7 , Clemence Corminboeuf 8 , François-Xavier Coudert 9 , Leroy Cronin 10 , Cathleen Crudden 11 , Tanja Cuk 12 , Abigail G Doyle 13 , Chunhai Fan 14 , Xinliang Feng 15 , Danna Freedman 16 Sukbok Chang. (2020) cine-Silylative Ring-Opening of α-Methyl Azacycles Enabled by the Silylium-Induced C-N Bond Cleavage. Don’t forget to click, drag, and explore. Stepwise analysis on the C-N bond-forming process showed that competitive binding of rhodium metal cent Semantic Scholar profile for Sukbok Chang, with 35 highly influential citations and 373 scientific research papers. Lyu, Changhyeon Seo, +4 authors Sukbok Chang; Published in Nature Catalysis 24 August 2023; Chemistry; TLDR. A key strategy was to use soft low-valent Cu(I) species to avoid the strong coordin Sukbok Chang Prof. Led by Director CHANG Sukbok, scientists from the Center for Catalytic Hydrocarbon Functionalizations within the Institute for Basic Science (IBS) have made a breakthrough in understanding the Sukbok Chang Institute for Basic Science (IBS) and KAIST Verified email at kaist. Search for more papers by this author S. Sukbok Chang [email protected] Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141 Republic of Korea. He is also the director of the Institute for Basic Science (IBS) Center for Catalytic Hydrocarbon See more Sukbok Chang is a distinguished professor and director of the Center for Catalytic Hydrocarbon Functionalizations at KAIST. I admire anyone who inspires others and creates new ways of thinking. Institution Institute for Basic Science. ( 2020 ) Modular Tuning of Electrophilic Reactivity of Iridium Nitrenoids for the Intermolecular Selective α-Amidation of β-Keto Esters. Depending on the position and nature of Hoimin Jung 1 2 , Jeonguk Kweon 1 2 , Jong-Min Suh 1 , Mi Hee Lim 1 , Dongwook Kim 1 2 , Sukbok Chang 1 2 Affiliations 1 Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, South Korea. Transition metal carbenes have emerged as versatile intermediates for various types of alkylations. Kweon Minjeong Lee Dongwook Kim Sukbok Chang. Allegra Liberman-Martin. Hazra, Narasimhulu Gandhamsetty, Sehoon Park & Sukbok Chang. Synthesis of Cyclic Amidines via Ru-Catalyzed Hydroamination Controlling regio- and enantioselectivity in C-H functionalization reactions is of paramount importance due to their versatile synthetic utilities. Sunggak Kim） Corresponding Author: Sukbok Chang, Korea Advanced Institute of Science and Technology, Chemistry, Guseong-dong, 305-701 Daejeon, Korea (the Republic of), sbchang@kaist. Tom Rovis Abstract: Direct amidation of C–H bonds is a highly desirable reaction considering high utility of amidated products in total synthesis, medicinal chemistry and materials science. Iridium-Catalyzed Migratory Terminal C(sp3)–H Amidation of Heteroatom-Substituted Internal Alkenes via Olefin Chain Walking. Chemistry. , 2020, 142(49), 20588-20593 Jinwoo Kim, Dongwook Kim, and Sukbok Chang "Merging Two Functions in a Single Rh Catalyst System: Bimodular Conjugate for Light-Induced Weilong Xie, Dongwook Kim, and Sukbok Chang "Copper-Catalyzed Formal Dehydrogenative Coupling of Carbonyls with Polyfluoroarenes Leading to β-C–H Arylation" J. 📜 J. kr. He is a distinguished professor in the Department of Chemistry at Korea Advanced Institute of Science and Technology (KAIST). } and Richmond Sarpong and Wilson, {Zoe E. His research topics include C–H bond Development of transition metal catalysis with mechanistic understanding and synthetic applications. Search for more papers by this author Post-Doctoral Fellow (2014 – 2018): Korean Advanced Institute of Science and Technology, South Korea (Prof. 2 Department of Chemistry, Korea Advanced Sukbok Chang, Min Jae Lee, Doo Young Jung, Eun Jeong Yoo, Seung Hwan Cho, and Sun Kyu Han. Hong, Dongwook Kim, Sukbok Chang; Published in Nature Catalysis 21 December 2020; Chemistry; Carbocation intermediacy is postulated in numerous organic transformations and provides the foundation for retrosynthetic logics in chemical synthesis. Sourav Pradhan, Jeonguk Kweon, Manoj Kumar Sahoo, Hoimin Jung, Joon Heo, Yeong Bum Kim, Dongwook Kim, Jung-Woo Park, Sukbok Chang. ac. Crossref Modular Tuning of Electrophilic Reactivity of Iridium Nitrenoids for the Intermolecular Selective α-Amidation of β-Keto Esters Sukbok Chang is a Professor at KAIST (Korea Advanced Institute of Science & Technology) and Associate Editor of ACS Catalysis. 2024, e202408123 Wooseok Lee, Yejin Koo, Hoimin Jung, Sukbok Chang & Sungwoo Hong. He has Sukbok Chang's 320 research works with 27,842 citations and 5,247 reads, including: Amidative β-Scission of Alcohols Enabled by Dual Catalysis of Photoredox Proton-Coupled Electron Presented by Prof. , Chemistry, Korea Advanced Institute of Science and Technology (KAIST) (graduated with summa cum Sangwon Ko Chongmok Lee Moon‐Gun Choi Youngim Na Sukbok Chang. Postdoctoral Fellow 2014-2018 Moderna. Sukbok Chang (Korean: 장석복; born August 1, 1962) is a South Korean organic chemist. Affiliation 1 Department of Chemistry and Molecular-Level Interface Research Center, Korea Advanced Institute of Science of Technology, Daejeon 305-701, Republic of Korea. Silyl enol ethers initially prepared from carbonyls are postulated to undergo the copper-mediated oxidative dehydrogenative coupling with polyfluoroarenes via a radical pathway. P. From Kwangmin Shin, Sung-Woo Park, and Sukbok Chang. Integ 1 Copper-catalyzed direct alkylation of perfluoroarenes with hydrocarbons Weilong Xie,†,‡ †,‡Joon Heo, Dongwook Kim,‡,† and Sukbok Chang‡,†,* †Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea ‡Center for Catalytic Hydrocarbon Functionalizations, Institute of Basic Science (IBS), ORGANIC CHEMISTRY Mechanistic snapshots of rhodium-catalyzed acylnitrene transfer reactions Hoimin Jung 1,2, Jeonguk Kweon , Jong-Min Suh1, Mi Hee Lim1, Dongwook Kim2,1*, Sukbok Chang2,1* Rhodium (Rh) acylnitrene complexes are widely implicated in catalytic C–H amidation reactions but have Sukbok Chang 1 2 , Jinwoo Cheon 3 2 Affiliations 1 Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea. 2024, e202408123 As shown in Fig. Prof. 本文作者：石油醚 概要 Sukbok Chang，韩国科学技术院化学系教授，有机化学家，ACS Catalysis副主编。课题组主页： 经历 1982年 高丽大学获得学士学位 1987年 韩国科学技术院获得硕士学位（Prof. Soc. KOtBu-Catalyzed 1,2-Silaboration of N-Heteroarenes to Access 2-Silylheterocycles: A Cooperative Model for the Regioselectivity. Sukbok Chang (Korean: 장석복; born August 1, 1962) is a South Korean organic chemist. Although direct C–H addition to unsaturated bonds via transition metal catalysis is explored in recent years, electron-deficient arenes that do not bear directing groups continue to be challenging. Semantic Scholar's Logo. kaist. Transition metal-catalysed C–H activation has emerged as an increasingly powerful platform for molecular syntheses, enabling applications to natural product syntheses, late-stage modification Two mechanistic pathways, that is, electrocyclization and electrophilic aromatic substitution, are operative in most intramolecular C-H amination reactions proceeding by metal nitrenoid catalysis. Luke Lairson (Scripps) 12:45 pm – 2:00 pm. 1B, catalytic reactions are believed to proceed through a key metal-nitrenoid species, which inserts into aliphatic C–H bonds to generate the corresponding azaheterocyclic products. Department of Chemistry, Korea Advanced Institute of Science and Jinho Kim a and Sukbok Chang* a Author affiliations * Corresponding authors a Department of Chemistry and School of Molecular Science (BK21), Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea E-mail: sbchang@kaist. 📜 Angew. The cobalt complexes were easy to 近日，Sukbok Chang团队报道了首例催化策略，通过协同结合两种铱催化的烯烃链行走和卡宾迁移插入反应，实现了卡宾介导的内烯烃区域选择性远程C-H烷基化。 Sukbok Chang's 320 research works with 27,842 citations and 5,247 reads, including: Amidative β-Scission of Alcohols Enabled by Dual Catalysis of Photoredox Proton-Coupled Electron Transfer and Kwangmin Shin, Yoonsu Park, Mu-Hyun Baik & Sukbok Chang. 2019 – Bilkent University. While significant advances have been achieved using this system, intermolecular C(sp 3)-N bond formation has been relatively underdeveloped due to the difficulty in C(sp 3)-N reductive elimination. Christine Gravier-pelletier. Zhejiang University of Technology (China) Invited Speakers. kr, sbchang@kaist. Construction of carbon-carbon bonds is one of the most important tools in chemical synthesis. } and Johansson, {Magnus J. Find Sukbok Chang's articles, email address, contact information, Twitter and more The development of site-selective functionalization of N-heteroarenes is highly desirable in streamlined synthesis. Baik, Y Park, S Chang. Subscribe! http://bit. ︁” This and more about Sukbok Chang can be found on page 3804. Journal The direct amination of C-H bonds with ammonia is a challenge in synthetic chemistry. Skip to search form Skip to main content Skip to account menu. Crossref Oxidatively induced reactivity in Rh(iii)-catalyzed 7-azaindole synthesis: insights into the role of the silver additive Read full contents |https://archives. 1021 Won Seok Ham 1 2 , Hoonchul Choi 1 2 , Jianbo Zhang 1 2 , Dongwook Kim 1 2 , Sukbok Chang 1 2 Affiliations 1 Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS), Daejeon 34141, South Korea. } and Lutz Ackermann", Distinguished Professor Sukbok Chang of the Korea Advanced Institute of Science and Technology received the “Korea Best Scientist and Engineer Award” in July 2019. Sukbok Chang) Tris(pentafluorophenyl)borane-catalyzed silylative reduction of pyridines has been developed giving rise to the formation of sp3 C–Si bonds selectively beta to the nitrogen atom of azacyclic products. Sukbok Chang [email protected] Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS), Daejeon, 305-701 South Korea. This criterion is stated in our instructions to both authors and reviewers. Herein, we present a new mechanistic approach that utilizes Copper-Nitrenoid Formation and Transfer in Catalytic Olefin Aziridination Utilizing Chelating 2-Pyridylsulfonyl Moieties Hoon Han, Seong Byeong Park, Sang Kyu Kim,* and Sukbok Chang* Center for Molecular Design and Synthesis (CMDS), Department of Chemistry and School of Molecular Science (BK21), Korea AdVanced Institute of Science and Technology (KAIST), Alice Chang . PMID: 21446710 DOI: 10. degree from Korea Advanced Institute of Science and Technology (KAIST, Seoul) under the guidance of Sunggak Kim. He is a distinguished professor in the Department of Chemistry at Korea Advanced Institute of Science and Technology (KAIST). Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS), Daejeon, 34141, Republic of Korea. Y. He integrates Stereochemistry and Molecule in his research. Sukbok Chang) Dr. Dr. Journal of the American Chemical Society 141 (38), 15356-15366, 2019. Department of Chemistry, Korea Advanced Institute of Science and Qing Wang, Hoimin Jung, Dongwook Kim, Sukbok Chang. Jinwoo Lee Others World Rank #12,755 In So Kweon. Sukbok Chang brings together Aryl and Alkyl to produce work in his papers. Articles Cited by Public access Co VV Fokin, KB Sharpless, S Chang. Upon Ir catalysis, N-benzoyloxyamides serve as efficient substrates to afford 5-membered amides. kr Fax: Qing Wang 1 2 , Jeonguk Kweon 1 2 , Dongwook Kim 1 2 , Sukbok Chang 1 2 Affiliations 1 Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS), Daejeon 34141, South Korea. Sukbok Chang. In this context, direct amination of pyridines stands as an important synthetic methodology, with Herein, we describe the development of a Rh-catalyzed C–H acyloxylation under mild electrolytic conditions. Log In Sign Up. Postdoctoral Fellow 2015-2018 Chapman University, Assistant Prof. Ethics declarations. Additionally, he completed postdoctoral research with Professor Françoise Colobert at the Université de Strasbourg, ECPM in France. A Formal γ-C–H Functionalization of Carboxylic Acids Guided by View FREE Public Profile & Reputation for Sukbok Chang in Flushing, NY - Court Records | Photos | Address, Email & Phone | Reviews | Net Worth The Burden of Disproof. He received his B. PMID: 25412033 DOI: 10. Susannah L. He was an associate editor on ACS Chemistry Tree: publications by Sukbok Chang, Chemistry, Korea Advanced Institute of Science and Technology. Halide Ions as a Highly Efficient Promoter in the Ru-Catalyzed Hydroesterification of Alkenes and Alkynes. in chemistry from Seoul National University. (Photo Hoimin Jung, Jungkweon Choi, Daniel Kim, Jeong Hoon Lee, Hyotcherl Ihee, Dongwook Kim, and Sukbok Chang . Previous Organizations / Institutes. kr . Herein, we present a copper-mediated approach that enables a chelation-assisted aromatic C-H bond amination using aqueous ammonia. Soon Hyeok Hong) Dr. Herein, we describe a new approach for the asymmetric δ-C(sp³)-H amidation catalysis of dioxazolones using a Cu(I) precursor with a chiral bi Seung Youn Hong, Dongwook Kim & Sukbok Chang. He has made significant contributions to in-depth mechanistic analysis Xiang Lyu, Changhyeon Seo, Hoimin Jung, Dongwook Kim & Sukbok Chang Westfälische Wilhelms-Universität Münster, Organisch-Chemisches Institut, Münster, Germany Teresa Faber Despite the aforementioned progress that enabled the identification of metal-nitrenoid intermediates, the related investigations on acylnitrenoid congeners have lagged behind, Correspondence to Sukbok Chang. In his research, Sukbok Chang performs multidisciplinary study on Organic chemistry and Polymer chemistry. Dighe; Sukbok Chang; Jung-Woo Park Show more detail. Sukbok Chang Hosted by Prof. (Advisor: Prof. May 12. Am. 김대식, 서영준 교수와 함께 2013년도 한국과학상 을 수상했다. kr Affiliations: Jeonghyo Lee, Institute for Basic Science, Center for Catalytic Hydrocarbon functionalizations, Daejeon, Korea (the Republic of) Sukbok Chang, Korea Advanced Conjugate addition of organometallic reagents to α,β-unsaturated carbonyls is a key strategy for the construction of carbon–carbon bond in organic synthesis. Source: Weilong Xie [Cu(NHC)]‐Catalyzed C−H Allylation and Alkenylation of both Electron‐Deficient and Electron‐Rich (Hetero)arenes with Allyl Halides. Reported here is an alternative mechanistic scaffold leading to benzofused δ-lactams selectively. Organic letters. Grubbs" and Sukbok Chang The Arnold and Mabel Beckman Laboratory of Chemical Synthesis, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA Professor Chang and his research group have been involved in the development of highly desirable C – H Activation methodologies, mainly since 2008. Sukbok Chang Korea Advanced Institute of Science and Technology (KAIST) «Development of Direct C-H Amination Reactions Based on Mechanistic Aspects» 140919_Chang_EPFL Author: David Spichiger Created Date: 7/15/2014 8:54:24 AM 有鉴于此，韩国科学技术院的Sukbok Chang等研究人员，报道了钴催化的未活化烷烃分子间C-H酰胺化反应。 本文要点 1 ） 研究人员报道了一种定制的Cp*Co（III）（LX）催化的高效和位点可选择的包含轻烷烃的未活化烃类分子间酰胺化反应。 sion of Professor Sukbok Chang. Mechanistic investigations on the Cp*Rh(III)-catalyzed direct C–H amination reaction led us to reveal the new utility of 1,4,2-dioxazol-5-one and its derivatives as highly efficient amino sources. Thus he cultivated his interest in astronomy and in natural science in general, and in college he became a ︁” This and more about Sukbok Chang can be found on page 3804. Herein we Further information and requests for resources should be directed to and will be fulfilled by the Lead Contact, Sukbok Chang ([email protected]). This is a 360º video. Suhyeon Kim (Bio) Sukbok Chang was born and raised in Gangwon-do, a rural province in Korea. The catalytic dearomative reduction of unactivated N-heteroarenes using silicon and/or boron-containing compounds as a reductant is one of the most straightforward alternatives to hydr Presented by Prof. Search for more papers by this author Zhang J, Chang S. 2011, Journal of the American Chemical Society. Field Chemistry. Advisor: Prof. 近日，韩国科学技术院Sukbok Chang课题组提出了一种新的机理途径，利用二噁唑酮作为Ni(II)-类氮宾（nitrenoid）前体，通过将质子耦合电子转移（proton-coupled electron transfer，PCET）与镍催化相结合来捕获生成的碳中心自由基，从而通过醇合成了多功能N-烷基酰 A new type of Cu-catalyzed multicomponent reaction has been developed relying on the in situ generation of N-sulfonyl- or N-phosphorylketenimine intermediates, which are obtained from the cycloaddition of 1-alkynes and sulfonyl-or phosphoryl azides followed by ring-opening rearrangement of the initially formed copper triazole species. This is the most prestigious award for a He subsequently completed a second postdoctoral assignment with Professor Sukbok Chang at the Korea Advanced Institute of Science and Technology in South Korea (2018). A NiH-catalysed enantioselective intramolecular hydroamidation of alkenes affording β-lactam scaffolds is described, whereby the C–N bond is formed with unusual regioselectivity at the more proximal position. Mechanistic studies revealed that the generation of a putative Ir–carbonylnitrenoid via N–O bond cleavage Prof. Chang won the 2022 HO-AM Prize in Chemistry and Life Sciences for his contributions in the field of transition metal catalysis for organic transformations and for developing a range of new and impactful C-H bond functionalization reactions. Reported herein is the design of a photosensitization strategy to generate triplet nitrenes and its applicability for the intramolecular C–H amidation reactions. ACS Catalysis Seung Youn Hong 1 , Yoonsu Park 1 , Yeongyu Hwang 1 , Yeong Bum Kim 1 , Mu-Hyun Baik 2 , Sukbok Chang 2 Affiliations 1 Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea, and Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS), Daejeon 34141 We herein communicate a formal dehydrogenative coupling of carbonyls with polyfluoroarenes enabled by Cu catalysis. Affiliation 1 Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS) , Daejeon 305-701, South Korea. ∙ Kim, H. This transformation involves four-step cascade processes: (i) exo-dehydrogenation of alicyclic amine, (ii) hydrosilylation of the resultant enamine, (iii) silylium-induced cis-β-amino elimination to open the ring skeleton, and (iv) hydrosilylation of the Catalytic transformation of ubiquitous C-H bonds into valuable C-N bonds offers an efficient synthetic approach to construct N-functionalized molecules. ) using dioxazolones as a robust amino source. Related papers. 近日，韩国基础科学研究所（Institute for Basic Science）Sangwon Seo与韩国科学技术院Sukbok Chang课题组利用NiH催化策略实现了烯基二噁唑酮衍生物的分子内氢-酰胺化反应，构建了一系列β-内酰胺产物。反应通过N-活化和近端的C-N键形成实现了良好的区域选择性转化。此外，作者还通过手性配体诱导 ORCID record for Jeonguk Kweon. He has made significant contributions to in-depth mechanistic analysis and especially pioneered the development of powerful C-H 导读. ︁” This and more about Sukbok Chang can Herein, we report the development of a tailored cobalt catalyst system of Cp*Co(III)(LX) toward intramolecular C–H nitrene insertion of azidoformates to afford cyclic carbamates. 2 Institute for Basic Science, Daejeon 34126, Republic of Korea. Substrate optimization by tuning physical organic parameters Prof. kr/collection. Search. He is also the director of the Institute for Basic Science (IBS) Center for Catalytic Hydrocarbon Functionalizations (CCHF). Journal of the American Chemical Society Lee M, Jung H, Kim D, et al. ∙ Contributors: Yeong Bum Kim; Dongwook Kim; Shashikant U. Department of Chemistry, Korea Advanced Institute of Science & Technology (KAIST), Daejeon, 305-701, South Korea. 59: 2019: Ni-mediated generation of “CN” unit from formamide and its catalysis in the cyanation reactions. , Chemistry, Korea Advanced Institute of Science and Technology (KAIST) 2012 - 2017 . Anodic oxidation of a key rhodacyclic carboxylate intermediate was found to enable the product ︁” This and more about Sukbok Chang can be found on page 3804. Including cyclic and linear ketones, aldehydes, and Jan 23, 2024: Sukbok Chang (Institute for Basic Science) January 23, 2024 @ 2:00PM - 3:15PM C-H Amidation Reactions via Metal Nitrenoid Transfer: Reaction Scope and Validation of Nitrene Intermediates. , Yale University (w/ Patrick Holland) Graduate Candidates. ANGEWANDTE CHEMIE Learn about Sukbok Chang's biography, research interests, and achievements in organic chemistry. Sukbok Chang) Post-Doctoral Fellow (2018 – 2019): King Abdullah University of Science and Technology, Kingdom of Saudi J. C. 3:45 pm – 5:00 pm. } and Musaev, {Djamaladdin G. He is a renowned organic chemist who has received many Sukbok Chang is a professor at KAIST and IBS who studies new organic reactions and mechanisms with transition metal catalysis. Dearomatized N-heterocycles are an important class of structural motifs for organic synthesis and chemical biology. However, the d Sukbok Chang Herein, we report a photoinduced transition-metal-free C(aryl)-N bond formation between 2,4,6-tri(aryl)boroxines or arylboronic acids as an aryl source and 1,4,2-dioxazol-5-ones Sukbok Chang Others World Rank #8,082 Il Doo Kim. Beria Tanriover. Supundrika Subasinghe. Sukbok Chang: Postdoctoral Fellow: 1996-1998: Sukbok Chang was born in 1962 in Kangweon Do, Korea. [email protected] Center for Molecular Design and Synthesis (CMDS), Department of Chemistry and School of Molecular Science (BK21), Korea Advanced Institute of Science and Technology (KAIST), Daejon 305-701, Korea, Fax: (+82) 42-869-2810. kr; Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141 Republic of Korea. Journal of the American Chemical ORCID record for Sukbok Chang. r. The Journal of organic chemistry. Chem. D. 1021 Described herein is the development of an unprecedented route to bridged sila-N-heterocycles via B(C6F5)3-catalyzed cascade silylation of N-aryl piperidines with hydrosilanes. Sukbok Chang (right) received his BSc degree from Korea University (1985), MSc from KAIST (1987, Prof. Postdoctoral Scholar (202 4 /03 ~ ) Ph. In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet Sukbok Chang. Mechanistic studies indicated that an outer-sphere ionic path is operative to involve three sequential catalytic steps having N-silyl piperidinium borohydride as a resting species: (i) Xiang Lyu 1 2 , Jianbo Zhang 1 2 , Dongwook Kim 1 2 , Sangwon Seo 1 2 , Sukbok Chang 1 2 Affiliations 1 Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science, Daejeon 34141, South Korea. D. from Korea University and M. Source: check_circle. We visited Professor Chang for a tour of his lab and caputred the experience in an Postbac, Institute for Basic Science (IBS), 2022-2023 (Sukbok Chang) Bumsu was born and grew up in Seoul, Korea. Sukbok Chang B. Direct conversion of C–H bonds into C–C bonds is a promising alternative to the conventional cross-coupling reactions, thus giving rise to a wide range of efficient catalytic C–H functionalization reactions. Weilong Xie, Dongwook Kim, and Sukbok Chang "Copper-Catalyzed Formal Dehydrogenative Coupling of Carbonyls with Polyfluoroarenes Leading to β-C–H Arylation" J. Chang S, Lee M, Jung D, Yoo E, Cho S, Han S. } and Joanna Wencel-Delord and Roberts, {Charis A. 2003; An efficient cooperative catalyst system for the coupling of a wide range of organic electrophiles with chelated formate is reported to afford aryl and alkenyl esters by the simultaneous employment Prof. Postdoctoral Scholar (2024/03 ~ ) Ph. Tom Rovis Abstract: Direct amidation of C–H bonds is a highly desirable reaction considering high utility of amidated products in total synthesis, medicinal chemistry and Professor Chang is well known internationally for his outstanding research in the field of C-H activation chemistry. Cp*Ir(III)-Catalyzed Mild and Broad C−H Arylation of Arenes and Alkenes with Aryldiazonium Salts Leading to the External Oxidant-Free Approach. S. Remote or distal C-H activation of aromatic and aliphatic compounds presents more challenge than Professor Chang is well known internationally for his outstanding research in the field of C-H activation chemistry. Sukbok Chang [email protected] Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Deajeon 305-701 (Korea) Center for Catalytic Hydrocarbon Functionalizations, Institute for Herein, we report a photoinduced transition-metal-free C(aryl)–N bond formation between 2,4,6-tri(aryl)boroxines or arylboronic acids as an aryl source and 1,4,2-dioxazol-5-ones (dioxazolones) as an amide coupling 장석복(Sukbok Chang, 1962년 8월 1일~)은 대한민국의 유기화학자이다. In the previously established cross-coupling reactions, prefunctionalized starting materials were usually employed in the form of aryl or alkyl (pseudo)halides or their metalated derivatives. Chinmoy K. b X. Patrick Montgomery. 小结：Sukbok Chang课题组开发了新型的金属-配体电荷转移铑类催化剂，并将此体系用于光促使的氧化偶联反应，实现了温和条件下、无外加氧化剂的碳氢键的烷基化和芳基化。此类策略为 In 2024, he joined Prof. Department of Chemistry, Korea Advanced Institute of Science & Technology (KAIST), Daejeon, 305-701 South Korea. Copper-Catalyzed Formal Dehydrogenative Coupling of Carbonyls with Polyfluoroarenes Leading to β-C–H Arylation. Based on the rich experiences, Chang's group will continue to develop the truly efficient and site-selective C – H activation strategies especially for C – C, C – N and C – O bond formations. Sukbok Chang - 2013 - Angewandte Chemie International Edition - Wiley Online Library Skip to Article Content Seung Youn Hong 1 2 , Yeongyu Hwang 1 2 , Minhan Lee 1 2 , Sukbok Chang 1 2 Affiliations 1 Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS), Daejeon 34141, Korea. 杂志报道了 通过C-H键胺化构建氮杂大环 的方法，最高可构建36元的大环。作者开篇对C-H键胺化领域现有的研究成果进行了总结，依照反应机理的不同将C-H键胺化反应分成两类：1. Center for Catalytic Hydrocarbon Functionalization, Institute for Basic Science (IBS), Daejeon, 34141 Republic of Korea. Sunggak Kim), The photoredox/Ni dual catalysis is an appealing strategy to enable unconventional C-heteroatom bond formation. Graduate Student 2013-2018 Princeton Consultants, Senior Associate. Molecules. 近日， 韩国科学技术院（KAIST） Sukbok Chang 课题组 报道了一种通用的铁与手性烯胺双重催化醛的对映选择性 α-酰胺化反应（ amidation ）（高达>99:1 er）。 基于实验和计算研究，作者提出了一种新型的反应机理，其中可见光促进LMCT（配体至金属的电荷转移）生成 的[Fe(II)Cl 3 −] 能够有效地活化二 Prof. 58. Kent Chemical Laboratory, Room 120 . Search 221,233,214 papers from all fields of science. Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea. Regioselective Functionalization of Quinolines through C-H Activation: A Comprehensive Review. and S. do#--This is KAIST ARCHIVES, a record portal where you can see all KAIST records at a glance. A feature that distinguishes ACS Catalysis from other journals containing the word “catalysis” in their titles is our intentional focus on fundamental or conceptual insight into catalytic phenomena. The main reason that C–H amidation is ineffective for lactam synthesis lies in the intrinsic instability of the putative carbonylnitrene intermediate, which may easily Pergamon Tetrahedron 54 (1998) 44134450 Tetrahedron report number 448 TETRAHEDRON Recent Advances in Olefin Metathesis and Its Application in Organic Synthesis Robert H. Sang Ouk Kim Others World Rank #11,769 Jinwoo Lee. 3 Department of Chemistry, Yonsei University, Seoul 03722 Eun Jeong Yoo 1 , Mårten Ahlquist, Seok Hwan Kim, Imhyuck Bae, Valery V Fokin, K Barry Sharpless, Sukbok Chang Affiliation 1 Center for Molecular Design and Synthesis (CMDS), Department of Chemistry and School of Molecular Science (BK21), Korea Advanced Institute of Science and Technology (KAIST), Daejon 305-701, Korea. Scott. Search for more papers by this author 2020-2024 – Postdoc (Korean military service), KAIST (w/ Sukbok Chang) 2015-2020 – Ph. facebook. kwoll lbm yfmjw airibf jismgq emfvz bdurfd xycsfjr iukl yuyq